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We study the effect of GSH and sexual dimorphism on acetaminophen toxicity by using a previously constructed model of acetaminophen metabolism [10]

This was done by first alkylating RSH, RSS and RS(S) n S with IAM (Fig

Contributed reagents, materials, and analysis tools: HW ZL QY

We review the physiological functions of glutathione, the limiting factors for its synthesis, as well as its clinical relevance, with particular emphasis on detoxification of environmental pollutants

Currently, AQ is forbidden for prophylactic use and is only prescribed in combination therapy with artesunate, as recommended by WHO (2015)